Harmonizome 3.0

methylthioadenosine phosphorylase

This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage pathway of both adenine and methionine. The encoded enzyme is deficient in many cancers. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2021]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mtap in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for MTAP from the Pathway Commons Protein-Protein Interactions dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the MTAP gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the MTAP gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the PNP/MTAP phosphorylase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Methylthioadenosine phosphorylase (MTAP) protein domain from the InterPro Predicted Protein Domain Annotations dataset.