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NEIL3 Genenei endonuclease VIII-like 3 (E. coli) NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008] |
neil3 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term neil3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
NEIL3 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for NEIL3 from the Pathway Commons Protein-Protein Interactions dataset. |
NEIL3 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the NEIL3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
Defective Base Excision Repair Associated with NEIL3 Gene Setproteins participating in the Defective Base Excision Repair Associated with NEIL3 pathway from the Reactome Pathways 2024 dataset. |
NEIL3-mediated resolution of ICLs Gene Setproteins participating in the NEIL3-mediated resolution of ICLs pathway from the Reactome Pathways 2024 dataset. |