Name

NR1D1 Gene

nuclear receptor subfamily 1, group D, member 1

This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes. [provided by RefSeq, Jan 2013]

nr1d1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nr1d1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NR1D1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NR1D1 from the Pathway Commons Protein-Protein Interactions dataset.

NR1D1 Gene Set

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the NR1D1 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

NR1D1 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the NR1D1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

NR1D1 (REV-ERBA) represses gene expression Gene Set

From Reactome Pathways 2024

proteins participating in the NR1D1 (REV-ERBA) represses gene expression pathway from the Reactome Pathways 2024 dataset.