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NTRK3 Geneneurotrophic tyrosine kinase, receptor, type 3 This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011] |
NTRK3-AS1 GeneNTRK3 antisense RNA 1 |
ntrk3 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term ntrk3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
NTRK3 Gene SetFrom KEA Substrates of Kinases substrates of the kinase NTRK3 from the curated KEA Substrates of Kinases dataset. |
NTRK3 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for NTRK3 from the Pathway Commons Protein-Protein Interactions dataset. |
NTRK3 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the NTRK3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
Activated NTRK3 signals through PI3K Gene Setproteins participating in the Activated NTRK3 signals through PI3K pathway from the Reactome Pathways 2024 dataset. |
Activated NTRK3 signals through PLCG1 Gene Setproteins participating in the Activated NTRK3 signals through PLCG1 pathway from the Reactome Pathways 2024 dataset. |
Activated NTRK3 signals through RAS Gene Setproteins participating in the Activated NTRK3 signals through RAS pathway from the Reactome Pathways 2024 dataset. |
NTF3 activates NTRK3 signaling Gene Setproteins participating in the NTF3 activates NTRK3 signaling pathway from the Reactome Pathways 2024 dataset. |
NTRK3 as a dependence receptor Gene Setproteins participating in the NTRK3 as a dependence receptor pathway from the Reactome Pathways 2024 dataset. |
Signaling by NTRK3 (TRKC) Gene Setproteins participating in the Signaling by NTRK3 (TRKC) pathway from the Reactome Pathways 2024 dataset. |