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NUMB Genenumb homolog (Drosophila) The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
numb Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term numb in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
NUMB Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for NUMB from the Pathway Commons Protein-Protein Interactions dataset. |
NUMB Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the NUMB gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
Numb/numb-like Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Numb/numb-like protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
NUMB-TP53-MDM2 complex Gene Setproteins in the NUMB-TP53-MDM2 complex protein complex from the CORUM Protein Complexes dataset. |
RalBP1-CCNB1-AP2A-NUMB-EPN1 complex Gene Setproteins in the RalBP1-CCNB1-AP2A-NUMB-EPN1 complex protein complex from the CORUM Protein Complexes dataset. |
NUMB domain Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the NUMB domain protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
BL6583 (NUMB) Gene Setproteins in the BL6583 (NUMB) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |
BL6582 (NUMB) Gene Setproteins in the BL6582 (NUMB) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |
Numb Chin Syndrome Gene SetFrom DisGeNET Gene-Disease Associations genes associated with the disease Numb Chin Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. |
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-geneSymbol_AR Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-geneSymbol_AR transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-geneSymbol_AR Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-geneSymbol_AR transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR Gene SetFrom Rummagene Transcription Factor Associations 2026 target genes of the PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR transcription factor from the Rummagene Transcription Factor Associations 2026 dataset. |