Harmonizome 3.0

paired box 2

PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pax2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From JASPAR Predicted Transcription Factor Targets

target genes of the PAX2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for PAX2 from the Pathway Commons Protein-Protein Interactions dataset.

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the PAX2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the PAX2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC3500769-srep00875-s3.xls-PAX2-Time_0_PAX2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC3500769-srep00875-s3.xls-PAX2-Time_1_PAX2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC3500769-srep00875-s3.xls-PAX2-Time_4_PAX2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC3500769-srep00875-s3.xls-PAX2-Time_24_PAX2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.