| Name |
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PPOX Geneprotoporphyrinogen oxidase This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
ppox Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term ppox in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
PPOX Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for PPOX from the Pathway Commons Protein-Protein Interactions dataset. |
PPOX Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the PPOX gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |