Harmonizome 3.0

prolactin receptor

This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term prlr in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for PRLR from the Pathway Commons Protein-Protein Interactions dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the PRLR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From CORUM Protein Complexes

proteins in the PRL receptor (PRLR) dimer complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Prolactin (PRL) - PRL receptor (PRLR) complex protein complex from the CORUM Protein Complexes dataset.