SC-28241 (MGMT)

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Results for "SC-28241 (MGMT)": 1 gene, 8 gene sets

Name
MGMT Gene O-6-methylguanine-DNA methyltransferase Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecule, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015]
SC-28241 (MGMT) Gene Set From NURSA Protein Complexes proteins in the SC-28241 (MGMT) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.
mgmt Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term mgmt in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
MGMT Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for MGMT from the Pathway Commons Protein-Protein Interactions dataset.
Mgmt-Methylated Glioblastoma Gene Set From DisGeNET Gene-Disease Associations genes associated with the disease Mgmt-Methylated Glioblastoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
Mgmt-Unmethylated Glioblastoma Gene Set From DisGeNET Gene-Disease Associations genes associated with the disease Mgmt-Unmethylated Glioblastoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
MGMT-mediated DNA damage reversal Gene Set From Reactome Pathways 2024 proteins participating in the MGMT-mediated DNA damage reversal pathway from the Reactome Pathways 2024 dataset.
MGMT methylation in smokers Gene Set From GWAS Catalog SNP-Phenotype Associations 2025 genes associated with the MGMT methylation in smokers phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.
MGMT Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the MGMT gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.