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SLC2A4 Genesolute carrier family 2 (facilitated glucose transporter), member 4 This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008] |
slc2a4 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term slc2a4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
SLC2A4 Gene SetFrom Hub Proteins Protein-Protein Interactions interacting proteins for hub protein SLC2A4 from the curated Hub Proteins Protein-Protein Interactions dataset. |
SLC2A4 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for SLC2A4 from the Pathway Commons Protein-Protein Interactions dataset. |
SLC2A4 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the SLC2A4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
SLC2A4 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the SLC2A4 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
Translocation of SLC2A4 (GLUT4) to the plasma membrane Gene Setproteins participating in the Translocation of SLC2A4 (GLUT4) to the plasma membrane pathway from the Reactome Pathways 2024 dataset. |