Harmonizome 3.0

transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)

Enables DNA-binding transcription factor binding activity; identical protein binding activity; and transcription corepressor activity. Involved in negative regulation of anoikis; negative regulation of signal transduction; and regulation of gene expression. Located in cytosol and nucleoplasm. Part of beta-catenin-TCF complex. [provided by Alliance of Genome Resources, Mar 2025]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tle1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for TLE1 from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the TLE1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From CORUM Protein Complexes

proteins in the TLE1-TLE2 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the HESX1-TLE1 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Lef1-Tle1 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the OCT1-OBF1-DNA-TLE1 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Lef1-Tle1-Ctnnb1 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the TLE1 homodimer complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the TLE1 corepressor complex (MASH1 promoter-corepressor complex) protein complex from the CORUM Protein Complexes dataset.