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TSPO Genetranslocator protein (18kDa) Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012] |
tspo Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term tspo in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
TSPO Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for TSPO from the Pathway Commons Protein-Protein Interactions dataset. |
TSPO Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the TSPO gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
TSPO Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the TSPO gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
TspO/MBR-related protein Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the TspO/MBR-related protein protein domain from the InterPro Predicted Protein Domain Annotations dataset. |