Harmonizome 3.0

YY1 transcription factor

YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1. [provided by RefSeq, Jul 2008]

YY1 associated protein 1

Predicted to enable transcription coregulator activity. Involved in cell differentiation; cell population proliferation; and regulation of cell cycle. Located in Ino80 complex; fibrillar center; and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

YY1 associated factor 2

This gene encodes a zinc finger containing protein that functions in the regulation of transcription. This protein was identified as an interacting partner of transcriptional repressor protein Yy1, and also interacts with other transcriptional regulators, including Myc and Polycomb. This protein can promote proteolysis of Yy1. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Feb 2016]

YY1 transcription factor pseudogene 1

YY1 transcription factor pseudogene 2

RING1 and YY1 binding protein

Enables nucleic acid binding activity. Involved in several processes, including negative regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of DNA-templated transcription; and positive regulation of apoptotic process. Located in nucleoplasm. Part of PcG protein complex. [provided by Alliance of Genome Resources, Mar 2025]

From ChEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the YY1-21170310-MESC-MOUSE transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

From ChEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the YY1-22570637-MALME-3M-HUMAN transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

From ChEA Transcription Factor Targets

target genes of the YY1 transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.

From CORUM Protein Complexes

proteins in the YY1-MDM2-p53 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the YY1-Notch1-RBP-Jkappa complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the YY1-Notch1 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the EED-EZH-YY1 polycomb complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Ku antigen-YY1-alphaMyHC promoter complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Yy1-Ppargc1a complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Yy1-Ppargc1a-Frap1 complex protein complex from the CORUM Protein Complexes dataset.

From ENCODE Transcription Factor Targets

target genes of the YY1 transcription factor in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term yy1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From JASPAR Predicted Transcription Factor Targets

target genes of the YY1 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.

From MotifMap Predicted Transcription Factor Targets

target genes of the YY1 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for YY1 from the Pathway Commons Protein-Protein Interactions dataset.

From ChEA Transcription Factor Targets 2022

target genes of the YY1-22570637-MALME-3M-HUMAN transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.

From ChEA Transcription Factor Targets 2022

target genes of the YY1-33199912-293T-HUMAN-KIDNEYEMBRYO transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the YY1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From JASPAR Predicted Mouse Transcription Factor Targets 2025

target genes of the Yy1 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2925 dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the YY1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.