Name

CGAS Gene

cyclic GMP-AMP synthase

Enables several functions, including 2',3'-cyclic GMP-AMP synthase activity; molecular condensate scaffold activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including defense response to symbiont; intracellular signal transduction; and regulation of defense response. Located in nuclear body; plasma membrane; and site of double-strand break. Is active in cytosol and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

cgas Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cgas in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CGAS Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the CGAS gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

CGAS Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the CGAS gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

negative regulation of cGAS/STING signaling pathway Gene Set

From GO Biological Process Annotations 2023

genes participating in the negative regulation of cGAS/STING signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

negative regulation of cGAS/STING signaling pathway Gene Set

From GO Biological Process Annotations 2025

genes participating in the negative regulation of cGAS/STING signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

positive regulation of cGAS/STING signaling pathway Gene Set

From GO Biological Process Annotations 2025

genes participating in the positive regulation of cGAS/STING signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

cGAS/STING signaling pathway Gene Set

From GO Biological Process Annotations 2025

genes participating in the cGAS/STING signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.