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MACC1 Genemetastasis associated in colon cancer 1 MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009] |
MACC1-AS1 GeneMACC1 antisense RNA 1 |
macc1 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term macc1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
MACC1 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for MACC1 from the Pathway Commons Protein-Protein Interactions dataset. |
MACC1 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the MACC1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |