Harmonizome 3.0

poly(A) binding protein, cytoplasmic 1

This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pabpc1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From NURSA Protein-Protein Interactions

interacting proteins for PABPC1 from the NURSA Protein-Protein Interactions dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for PABPC1 from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the PABPC1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From CORUM Protein Complexes

proteins in the PABPC1-HSPA8-HNRPD-EIF4G1 complex protein complex from the CORUM Protein Complexes dataset.