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PPIB Genepeptidylprolyl isomerase B (cyclophilin B) The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009] |
ppib Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term ppib in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
PPIB Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for PPIB from the Pathway Commons Protein-Protein Interactions dataset. |
PPIB Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the PPIB gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
PPIB Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the PPIB gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |