Harmonizome 3.0

B-cell CLL/lymphoma 2

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term bcl2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein BCL2 from the curated Hub Proteins Protein-Protein Interactions dataset.

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for BCL2 from the MSigDB Cancer Gene Co-expression Modules dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for BCL2 from the Pathway Commons Protein-Protein Interactions dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the BCL2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From CORUM Protein Complexes

proteins in the CALM1-FKBP38-BCL2 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the BAR-BCL2-CASP8 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Bcl2 homodimer complex protein complex from the CORUM Protein Complexes dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Bcl2-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Bcl2-/adenovirus E1B 19kDa-interacting protein 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease High-Grade B-Cell Lymphoma, With Myc And Bcl2 And/Or Bcl6 Rearrangements in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the Perturb_1245_OE_MYC/BCL2/BCL6_SRP376326 gene perturbation from the PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC6778131-41467_2019_12494_MOESM13_ESM.xlsx-Figure_S3b-BCL2-MYC_Day_75_MYC transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.