CYP1A2

Filters:

Results for "CYP1A2": 1 gene, 8 gene sets

Name
CYP1A2 Gene cytochrome P450, family 1, subfamily A, polypeptide 2 This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008]
cyp1a2 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term cyp1a2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
CYP1A2 Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for CYP1A2 from the Pathway Commons Protein-Protein Interactions dataset.
CYP1A2 Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the CYP1A2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
cyp1a2 activity Gene Set From GAD Gene-Disease Associations genes associated with the disease cyp1a2 activity in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
cyp1a2 enzymatic activity Gene Set From GAD Gene-Disease Associations genes associated with the disease cyp1a2 enzymatic activity in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 Gene Set From Reactome Pathways 2014 proteins participating in the Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 pathway from the Reactome Pathways dataset.
Cyp1A2 Polymorphism Gene Set From DisGeNET Gene-Disease Associations genes associated with the disease Cyp1A2 Polymorphism in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.
Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 Gene Set From Reactome Pathways 2024 proteins participating in the Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2 pathway from the Reactome Pathways 2024 dataset.