Harmonizome 3.0

DGCR8 microprocessor complex subunit

This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term dgcr8 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for DGCR8 from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the DGCR8 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From CORUM Protein Complexes

proteins in the DGCR8-NCL complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the DGCR8-ILF3 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the DGCR8 multiprotein complex protein complex from the CORUM Protein Complexes dataset.

From NURSA Protein Complexes

proteins in the BL8964 (DGCR8) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.