Harmonizome 3.0

homeobox B13

This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region. [provided by RefSeq, Jul 2008]

Ets2 repressor factor

ETS2 is a transcription factor and protooncogene involved in development, apoptosis, and the regulation of telomerase. The protein encoded by this gene binds to the ETS2 promoter and is a strong repressor of ETS2 transcription. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the ERF::HOXB13 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term hoxb13 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for HOXB13 from the Pathway Commons Protein-Protein Interactions dataset.

From ChEA Transcription Factor Targets 2022

target genes of the HOXB13-26457646-LNCAP-HUMAN-PROSTATE-CARCINOMA transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the HOXB13 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the HOXB13-Related Cancer Predisposition phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the ELK1::HOXB13 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the ETV2::HOXB13 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the HOXB13 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the HOXB13 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term erf in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From NURSA Protein Complexes

proteins in the BL6486 (ERF) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

From NURSA Protein Complexes

proteins in the BL6487 (ERF) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for ERF from the Pathway Commons Protein-Protein Interactions dataset.

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the ERF transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the ERF::FIGLA transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the ERF::FOXI1 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the ERF::FOXO1 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the ERF::NHLH1 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the ERF::SREBF2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the ERF gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.