Harmonizome 3.0

forkhead box A2

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]

From ChEA Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the FOXA2-19822575-HepG2-human transcription factor binding site profile from the CHEA Transcription Factor Binding Site Profiles dataset.

From ChEA Transcription Factor Targets 2022

target genes of the FOXA2-19822575-HEPG2-HUMAN transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets 2022 dataset.

From ChEA Transcription Factor Targets

target genes of the FOXA2 transcription factor in low- or high-throughput transcription factor functional studies from the CHEA Transcription Factor Targets dataset.

From ENCODE Transcription Factor Targets

target genes of the FOXA2 transcription factor in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term foxa2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From JASPAR Predicted Transcription Factor Targets

target genes of the FOXA2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for FOXA2 from the Pathway Commons Protein-Protein Interactions dataset.

From PID Pathways

proteins participating in the FOXA2 and FOXA3 transcription factor networks pathway from the PID Pathways dataset.

From WikiPathways Pathways 2024

proteins participating in the FOXA2 pathway pathway from the WikiPathways Pathways 2024 dataset.

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the FOXA2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC12119949-41467_2025_60269_MOESM3_ESM.xlsx-FOXA2-TR_FOXA2 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the FOXA2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.