Harmonizome 3.0

forkhead box O4

This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term foxo4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From NURSA Protein-Protein Interactions

interacting proteins for FOXO4 from the NURSA Protein-Protein Interactions dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for FOXO4 from the Pathway Commons Protein-Protein Interactions dataset.

From JASPAR Predicted Human Transcription Factor Targets 2025

target genes of the FOXO4 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the FOXO4 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From CORUM Protein Complexes

proteins in the SMAD3-SMAD4-FOXO4 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Foxo4-Srf-Myocd complex protein complex from the CORUM Protein Complexes dataset.

From NURSA Protein Complexes

proteins in the SC-25359 (FOXO4) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.