Harmonizome 3.0

frizzled class receptor 2

This intronless gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway. Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways. [provided by RefSeq, Dec 2010]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term fzd2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for FZD2 from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the FZD2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From Reactome Pathways 2014

proteins participating in the WNT5A-dependent internalization of FZD2, FZD5 and ROR2 pathway from the Reactome Pathways dataset.

From Reactome Pathways 2024

proteins participating in the WNT5A-dependent internalization of FZD2, FZD5 and ROR2 pathway from the Reactome Pathways 2024 dataset.