Harmonizome 3.0

guanine nucleotide binding protein (G protein), q polypeptide

This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term gnaq in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for GNAQ from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the GNAQ gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From CORUM Protein Complexes

proteins in the GNAQ-GEFT-RHOA complex protein complex from the CORUM Protein Complexes dataset.

From WikiPathways Pathways 2024

proteins participating in the GNAQ pathways in port wine stain pathway from the WikiPathways Pathways 2024 dataset.