HUS1

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Results for "HUS1": 1 gene, 9 gene sets

Name
HUS1 Gene HUS1 checkpoint homolog (S. pombe) The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]
hus1 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term hus1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
HUS1 Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for HUS1 from the Pathway Commons Protein-Protein Interactions dataset.
HUS1 Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the HUS1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
HUS1 Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the HUS1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
RAD9-RAD1-HUS1-POLB complex Gene Set From CORUM Protein Complexes proteins in the RAD9-RAD1-HUS1-POLB complex protein complex from the CORUM Protein Complexes dataset.
RAD9-RAD1-HUS1-APE1 complex Gene Set From CORUM Protein Complexes proteins in the RAD9-RAD1-HUS1-APE1 complex protein complex from the CORUM Protein Complexes dataset.
Rad9, Rad1, Hus1-interacting nuclear orphan protein 1 Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Rad9, Rad1, Hus1-interacting nuclear orphan protein 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Cell cycle checkpoint, Hus1 Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Cell cycle checkpoint, Hus1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Checkpoint protein Hus1/Mec3 Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Checkpoint protein Hus1/Mec3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.