Lymphotoxin-alpha

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Results for "Lymphotoxin-alpha": 3 genes, 15 gene sets

Name
LTBR Gene lymphotoxin beta receptor (TNFR superfamily, member 3) This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012]
LTB Gene lymphotoxin beta (TNF superfamily, member 3) Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
LTA Gene lymphotoxin alpha The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
Lymphotoxin-alpha Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Lymphotoxin-alpha protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Lymphotoxin beta receptor complex Gene Set From CORUM Protein Complexes proteins in the Lymphotoxin beta receptor complex protein complex from the CORUM Protein Complexes dataset.
lymphotoxin Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term lymphotoxin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
positive regulation of lymphotoxin a biosynthetic process Gene Set From GO Biological Process Annotations 2015 genes participating in the positive regulation of lymphotoxin a biosynthetic process biological process from the curated GO Biological Process Annotations 2015 dataset.
lymphotoxin a biosynthetic process Gene Set From GO Biological Process Annotations 2015 genes participating in the lymphotoxin a biosynthetic process biological process from the curated GO Biological Process Annotations 2015 dataset.
positive regulation of lymphotoxin a production Gene Set From GO Biological Process Annotations 2015 genes participating in the positive regulation of lymphotoxin a production biological process from the curated GO Biological Process Annotations 2015 dataset.
regulation of lymphotoxin a biosynthetic process Gene Set From GO Biological Process Annotations 2015 genes participating in the regulation of lymphotoxin a biosynthetic process biological process from the curated GO Biological Process Annotations 2015 dataset.
regulation of lymphotoxin a production Gene Set From GO Biological Process Annotations 2015 genes participating in the regulation of lymphotoxin a production biological process from the curated GO Biological Process Annotations 2015 dataset.
Lymphotoxin-beta Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Lymphotoxin-beta protein domain from the InterPro Predicted Protein Domain Annotations dataset.
positive regulation of lymphotoxin A production Gene Set From GO Biological Process Annotations 2023 genes participating in the positive regulation of lymphotoxin A production biological process from the curated GO Biological Process Annotations 2023 dataset.
regulation of lymphotoxin A production Gene Set From GO Biological Process Annotations 2023 genes participating in the regulation of lymphotoxin A production biological process from the curated GO Biological Process Annotations 2023 dataset.
positive regulation of lymphotoxin A production Gene Set From GO Biological Process Annotations 2025 genes participating in the positive regulation of lymphotoxin A production biological process from the curated GO Biological Process Annotations 2025 dataset.
regulation of lymphotoxin A production Gene Set From GO Biological Process Annotations 2025 genes participating in the regulation of lymphotoxin A production biological process from the curated GO Biological Process Annotations 2025 dataset.
Lymphotoxin complex Gene Set From COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 proteins co-occuring with the Lymphotoxin complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.
RECOMBINANT LYMPHOTOXIN BETA Gene Set From DGIdb Drug Targets 2026 interacting proteins for the RECOMBINANT LYMPHOTOXIN BETA drug from theDGIdb Drug Targets 2026 dataset.