MAPK1

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Results for "MAPK1": 1 gene, 12 gene sets

Name
MAPK1 Gene mitogen-activated protein kinase 1 This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]
mapk1 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term mapk1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
MAPK1 Gene Set From Hub Proteins Protein-Protein Interactions interacting proteins for hub protein MAPK1 from the curated Hub Proteins Protein-Protein Interactions dataset.
MAPK1 Gene Set From KEA Substrates of Kinases substrates of the kinase MAPK1 from the curated KEA Substrates of Kinases dataset.
MAPK1 Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for MAPK1 from the Pathway Commons Protein-Protein Interactions dataset.
MAPK1 Gene Set From PhosphoSitePlus Substrates of Kinases substrates of the kinase MAPK1 from the curated PhosphoSitePlus Substrates of Kinases dataset.
MAPK1 Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the MAPK1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
MAPK1 Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the MAPK1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
EPI-1586-1 (MAPK1) Gene Set From NURSA Protein Complexes proteins in the EPI-1586-1 (MAPK1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.
MAP3K8 (TPL2)-dependent MAPK1/3 activation Gene Set From Reactome Pathways 2024 proteins participating in the MAP3K8 (TPL2)-dependent MAPK1/3 activation pathway from the Reactome Pathways 2024 dataset.
MAPK1 (ERK2) activation Gene Set From Reactome Pathways 2024 proteins participating in the MAPK1 (ERK2) activation pathway from the Reactome Pathways 2024 dataset.
MAPK1/MAPK3 signaling Gene Set From Reactome Pathways 2024 proteins participating in the MAPK1/MAPK3 signaling pathway from the Reactome Pathways 2024 dataset.
RAF-independent MAPK1/3 activation Gene Set From Reactome Pathways 2024 proteins participating in the RAF-independent MAPK1/3 activation pathway from the Reactome Pathways 2024 dataset.