NR1H2

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Results for "NR1H2": 1 gene, 13 gene sets

Name
NR1H2 Gene nuclear receptor subfamily 1, group H, member 2 The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]
nr1h2 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term nr1h2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
NR1H2 Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for NR1H2 from the Pathway Commons Protein-Protein Interactions dataset.
Nr1h2 Gene Set From JASPAR Predicted Mouse Transcription Factor Targets 2025 target genes of the Nr1h2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2925 dataset.
NR1H2 Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the NR1H2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
NR1H2::RXRA Gene Set From MotifMap Predicted Transcription Factor Targets target genes of the NR1H2::RXRA transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis Gene Set From Reactome Pathways 2024 proteins participating in the NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis pathway from the Reactome Pathways 2024 dataset.
NR1H2 & NR1H3 regulate gene expression linked to lipogenesis Gene Set From Reactome Pathways 2024 proteins participating in the NR1H2 & NR1H3 regulate gene expression linked to lipogenesis pathway from the Reactome Pathways 2024 dataset.
NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose Gene Set From Reactome Pathways 2024 proteins participating in the NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose pathway from the Reactome Pathways 2024 dataset.
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis Gene Set From Reactome Pathways 2024 proteins participating in the NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis pathway from the Reactome Pathways 2024 dataset.
NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake Gene Set From Reactome Pathways 2024 proteins participating in the NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake pathway from the Reactome Pathways 2024 dataset.
NR1H2 and NR1H3-mediated signaling Gene Set From Reactome Pathways 2024 proteins participating in the NR1H2 and NR1H3-mediated signaling pathway from the Reactome Pathways 2024 dataset.
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux Gene Set From Reactome Pathways 2024 proteins participating in the NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux pathway from the Reactome Pathways 2024 dataset.
NR1H2::RXRA Gene Set From JASPAR Predicted Human Transcription Factor Targets 2025 target genes of the NR1H2::RXRA transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Human Transcription Factor Targets dataset.