Harmonizome 3.0

neuropilin 2

This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells. [provided by RefSeq, Jul 2021]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nrp2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for NRP2 from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the NRP2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From CORUM Protein Complexes

proteins in the NRP2-VEGFR3 complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the NRP2-VEGFD complex, heparin dependent protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the NRP2-VEGFC complex protein complex from the CORUM Protein Complexes dataset.