Name

NTRK2 Gene

neurotrophic tyrosine kinase, receptor, type 2

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

ntrk2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ntrk2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NTRK2 Gene Set

From KEA Substrates of Kinases

substrates of the kinase NTRK2 from the curated KEA Substrates of Kinases dataset.

NTRK2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NTRK2 from the Pathway Commons Protein-Protein Interactions dataset.

NTRK2 Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase NTRK2 from the curated PhosphoSitePlus Substrates of Kinases dataset.

NTRK2 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the NTRK2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

NTRK2_drugactivation_66_GSE20358 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the NTRK2_drugactivation_66_GSE20358 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.