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ORC5 Geneorigin recognition complex, subunit 5 The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Oct 2010] |
ORC5 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for ORC5 from the Pathway Commons Protein-Protein Interactions dataset. |
ORC5 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the ORC5 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
ORC5-ORC1 complex Gene Setproteins in the ORC5-ORC1 complex protein complex from the CORUM Protein Complexes dataset. |