Name

PIF1 Gene

PIF1 5'-to-3' DNA helicase

This gene encodes a DNA-dependent adenosine triphosphate (ATP)-metabolizing enzyme that functions as a 5' to 3' DNA helicase. The encoded protein can resolve G-quadruplex structures and RNA-DNA hybrids at the ends of chromosomes. It also prevents telomere elongation by inhibiting the actions of telomerase. Alternative splicing and the use of alternative start codons results in multiple isoforms that are differentially localized to either the mitochondria or the nucleus. [provided by RefSeq, Nov 2013]

PIF1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PIF1 from the Pathway Commons Protein-Protein Interactions dataset.

PIF1 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the PIF1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

DNA helicase Pif1 like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA helicase Pif1 like protein domain from the InterPro Predicted Protein Domain Annotations dataset.