Name

PLXNA1 Gene

plexin A1

Predicted to enable semaphorin receptor activity. Predicted to be involved in several processes, including T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; nervous system development; and positive regulation of axonogenesis. Predicted to act upstream of or within dichotomous subdivision of terminal units involved in salivary gland branching; neuron projection extension; and regulation of smooth muscle cell migration. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

PLXNA1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PLXNA1 from the Pathway Commons Protein-Protein Interactions dataset.

PLXNA1 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the PLXNA1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

PLXNA1 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the PLXNA1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

PLXNA1-RANBPM complex Gene Set

From CORUM Protein Complexes

proteins in the PLXNA1-RANBPM complex protein complex from the CORUM Protein Complexes dataset.

PLXNA1-related neurodevelopmental disorder Gene Set

From ClinVar Gene-Phenotype Associations 2025

genes associated with the PLXNA1-related neurodevelopmental disorder phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.