Name

PTGS2 Gene

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]

ptgs2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ptgs2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PTGS2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PTGS2 from the Pathway Commons Protein-Protein Interactions dataset.

PTGS2 homodimer complex Gene Set

From CORUM Protein Complexes

proteins in the PTGS2 homodimer complex protein complex from the CORUM Protein Complexes dataset.