Name

PFAS Gene

phosphoribosylformylglycinamidine synthase

Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis. [provided by RefSeq, Jul 2008]

MTHFS Gene

5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)

The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

Phosphoribosylformylglycinamidine cyclo-ligase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Phosphoribosylformylglycinamidine cyclo-ligase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

phosphoribosylformylglycinamidine synthase activity Gene Set

From GO Molecular Function Annotations 2015

genes performing the phosphoribosylformylglycinamidine synthase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

Phosphoribosylformylglycinamidine synthase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Phosphoribosylformylglycinamidine synthase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

phosphoribosylformylglycinamidine synthase activity Gene Set

From GO Molecular Function Annotations 2023

genes performing the phosphoribosylformylglycinamidine synthase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

phosphoribosylformylglycinamidine synthase activity Gene Set

From GO Molecular Function Annotations 2025

genes performing the phosphoribosylformylglycinamidine synthase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide from the curated CTD Gene-Chemical Interactions dataset.

cyclo-L-glycyl-L-2-allylproline Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical cyclo-L-glycyl-L-2-allylproline from the curated CTD Gene-Chemical Interactions dataset.

1,3-dihydroxy-2-hydroxymethylpropyl-2-ammonium 2-((R)-3-cyclo-hexyl-1-phenylpropyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylate monohydrate Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical 1,3-dihydroxy-2-hydroxymethylpropyl-2-ammonium 2-((R)-3-cyclo-hexyl-1-phenylpropyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylate monohydrate from the curated CTD Gene-Chemical Interactions dataset.

dynorphin A-(1-11)-NH2, Nalpha-benzylTyr(1)-cyclo(Asp(5)-Dap(8))- Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical dynorphin A-(1-11)-NH2, Nalpha-benzylTyr(1)-cyclo(Asp(5)-Dap(8))- from the curated CTD Gene-Chemical Interactions dataset.

cyclo(leucylglycine) Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical cyclo(leucylglycine) from the curated CTD Gene-Chemical Interactions dataset.

cyclo(Trp-Asp-Pro-Val-Leu) Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical cyclo(Trp-Asp-Pro-Val-Leu) from the curated CTD Gene-Chemical Interactions dataset.

8,5'-cyclo-2'-deoxyadenosine Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical 8,5'-cyclo-2'-deoxyadenosine from the curated CTD Gene-Chemical Interactions dataset.

cyclo(Gln-Trp-Phe-Gly-Leu-Met) Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical cyclo(Gln-Trp-Phe-Gly-Leu-Met) from the curated CTD Gene-Chemical Interactions dataset.

cyclo apelin-12 (1-12) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the cyclo apelin-12 (1-12) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

cyclo apelin-12 (7-12) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the cyclo apelin-12 (7-12) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

cyclo(7-12) Des-AA1 2 5-[Glu7 D-Trp8 IAmp9 m-I-Tyr11 hhLys12]SRIF Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the cyclo(7-12) Des-AA1 2 5-[Glu7 D-Trp8 IAmp9 m-I-Tyr11 hhLys12]SRIF ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

CYCLO APELIN-12 (1-12) Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the CYCLO APELIN-12 (1-12) drug from theDGIdb Drug Targets 2026 dataset.

CYCLO APELIN-12 (7-12) Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the CYCLO APELIN-12 (7-12) drug from theDGIdb Drug Targets 2026 dataset.

CYCLO(7-12) DES-AA1,2,5-[GLU7,D-TRP8,IAMP9,M-I-TYR11,HHLYS12]SRIF Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the CYCLO(7-12) DES-AA1,2,5-[GLU7,D-TRP8,IAMP9,M-I-TYR11,HHLYS12]SRIF drug from theDGIdb Drug Targets 2026 dataset.