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PFAS Genephosphoribosylformylglycinamidine synthase Purines are necessary for many cellular processes, including DNA replication, transcription, and energy metabolism. Ten enzymatic steps are required to synthesize inosine monophosphate (IMP) in the de novo pathway of purine biosynthesis. The enzyme encoded by this gene catalyzes the fourth step of IMP biosynthesis. [provided by RefSeq, Jul 2008] |
MTHFS Gene5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011] |
Phosphoribosylformylglycinamidine cyclo-ligase Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Phosphoribosylformylglycinamidine cyclo-ligase protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
phosphoribosylformylglycinamidine synthase activity Gene SetFrom GO Molecular Function Annotations 2015 genes performing the phosphoribosylformylglycinamidine synthase activity molecular function from the curated GO Molecular Function Annotations 2015 dataset. |
Phosphoribosylformylglycinamidine synthase Gene SetFrom InterPro Predicted Protein Domain Annotations proteins predicted to have the Phosphoribosylformylglycinamidine synthase protein domain from the InterPro Predicted Protein Domain Annotations dataset. |
phosphoribosylformylglycinamidine synthase activity Gene SetFrom GO Molecular Function Annotations 2023 genes performing the phosphoribosylformylglycinamidine synthase activity molecular function from the curated GO Molecular Function Annotations 2023 dataset. |
phosphoribosylformylglycinamidine synthase activity Gene SetFrom GO Molecular Function Annotations 2025 genes performing the phosphoribosylformylglycinamidine synthase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset. |
phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide from the curated CTD Gene-Chemical Interactions dataset. |
cyclo-L-glycyl-L-2-allylproline Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical cyclo-L-glycyl-L-2-allylproline from the curated CTD Gene-Chemical Interactions dataset. |
1,3-dihydroxy-2-hydroxymethylpropyl-2-ammonium 2-((R)-3-cyclo-hexyl-1-phenylpropyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylate monohydrate Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical 1,3-dihydroxy-2-hydroxymethylpropyl-2-ammonium 2-((R)-3-cyclo-hexyl-1-phenylpropyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylate monohydrate from the curated CTD Gene-Chemical Interactions dataset. |
dynorphin A-(1-11)-NH2, Nalpha-benzylTyr(1)-cyclo(Asp(5)-Dap(8))- Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical dynorphin A-(1-11)-NH2, Nalpha-benzylTyr(1)-cyclo(Asp(5)-Dap(8))- from the curated CTD Gene-Chemical Interactions dataset. |
cyclo(leucylglycine) Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical cyclo(leucylglycine) from the curated CTD Gene-Chemical Interactions dataset. |
cyclo(Trp-Asp-Pro-Val-Leu) Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical cyclo(Trp-Asp-Pro-Val-Leu) from the curated CTD Gene-Chemical Interactions dataset. |
8,5'-cyclo-2'-deoxyadenosine Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical 8,5'-cyclo-2'-deoxyadenosine from the curated CTD Gene-Chemical Interactions dataset. |
cyclo(Gln-Trp-Phe-Gly-Leu-Met) Gene SetFrom CTD Gene-Chemical Interactions genes/proteins interacting with the chemical cyclo(Gln-Trp-Phe-Gly-Leu-Met) from the curated CTD Gene-Chemical Interactions dataset. |
cyclo apelin-12 (1-12) Gene SetFrom Guide to Pharmacology Chemical Ligands of Receptors receptors of the cyclo apelin-12 (1-12) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset. |
cyclo apelin-12 (7-12) Gene SetFrom Guide to Pharmacology Chemical Ligands of Receptors receptors of the cyclo apelin-12 (7-12) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset. |
cyclo(7-12) Des-AA1 2 5-[Glu7 D-Trp8 IAmp9 m-I-Tyr11 hhLys12]SRIF Gene SetFrom Guide to Pharmacology Chemical Ligands of Receptors receptors of the cyclo(7-12) Des-AA1 2 5-[Glu7 D-Trp8 IAmp9 m-I-Tyr11 hhLys12]SRIF ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset. |
CYCLO APELIN-12 (1-12) Gene Setinteracting proteins for the CYCLO APELIN-12 (1-12) drug from theDGIdb Drug Targets 2026 dataset. |
CYCLO APELIN-12 (7-12) Gene Setinteracting proteins for the CYCLO APELIN-12 (7-12) drug from theDGIdb Drug Targets 2026 dataset. |
CYCLO(7-12) DES-AA1,2,5-[GLU7,D-TRP8,IAMP9,M-I-TYR11,HHLYS12]SRIF Gene Setinteracting proteins for the CYCLO(7-12) DES-AA1,2,5-[GLU7,D-TRP8,IAMP9,M-I-TYR11,HHLYS12]SRIF drug from theDGIdb Drug Targets 2026 dataset. |