Harmonizome 3.0

RAD1 checkpoint DNA exonuclease

This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jan 2009]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term rad1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From NURSA Protein-Protein Interactions

interacting proteins for RAD1 from the NURSA Protein-Protein Interactions dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for RAD1 from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the RAD1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From CORUM Protein Complexes

proteins in the RAD9-RAD1-HUS1-POLB complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the RAD9-RAD1-HUS1-APE1 complex protein complex from the CORUM Protein Complexes dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Rad9, Rad1, Hus1-interacting nuclear orphan protein 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Cell cycle checkpoint protein, Rad1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Rad1/Rec1/Rad17 protein domain from the InterPro Predicted Protein Domain Annotations dataset.