Name

RHOH Gene

ras homolog family member H

The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013]

rhoh Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term rhoh in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

RHOH Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for RHOH from the Pathway Commons Protein-Protein Interactions dataset.

RHOH Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the RHOH gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

RHOH Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the RHOH gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

RHOH GTPase cycle Gene Set

From Reactome Pathways 2024

proteins participating in the RHOH GTPase cycle pathway from the Reactome Pathways 2024 dataset.