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Results for "RNF8": 1 gene, 4 gene sets

Name

RNF8 Gene

ring finger protein 8, E3 ubiquitin protein ligase

The protein encoded by this gene contains a RING finger motif and an FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. This protein is also known to play a role in the DNA damage response and depletion of this protein causes cell growth inhibition and cell cycle arrest. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

rnf8 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term rnf8 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

RNF8 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for RNF8 from the Pathway Commons Protein-Protein Interactions dataset.

RNF8 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the RNF8 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

E3 ubiquitin-protein ligase RNF8 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the E3 ubiquitin-protein ligase RNF8 protein domain from the InterPro Predicted Protein Domain Annotations dataset.