Harmonizome 3.0

sorting nexin 1

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term snx1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for SNX1 from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the SNX1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From CORUM Protein Complexes

proteins in the Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26A) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Retromer complex (SNX1, SNX2, VPS35, VPS29, VPS26B) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the SNX complex (SNX1, SNX6) protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the SNX complex (SNX1,1a,2,4, PDGF receptor) protein complex from the CORUM Protein Complexes dataset.