TLR5

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Results for "TLR5": 1 gene, 7 gene sets

Name
TLR5 Gene toll-like receptor 5 This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]
tlr5 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term tlr5 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
TLR5 Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for TLR5 from the Pathway Commons Protein-Protein Interactions dataset.
TLR5 Gene Set From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the TLR5 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
Toll Like Receptor 5 (TLR5) Cascade Gene Set From Reactome Pathways 2014 proteins participating in the Toll Like Receptor 5 (TLR5) Cascade pathway from the Reactome Pathways dataset.
IRAK4 deficiency (TLR5) Gene Set From Reactome Pathways 2024 proteins participating in the IRAK4 deficiency (TLR5) pathway from the Reactome Pathways 2024 dataset.
MyD88 deficiency (TLR5) Gene Set From Reactome Pathways 2024 proteins participating in the MyD88 deficiency (TLR5) pathway from the Reactome Pathways 2024 dataset.
Toll Like Receptor 5 (TLR5) Cascade Gene Set From Reactome Pathways 2024 proteins participating in the Toll Like Receptor 5 (TLR5) Cascade pathway from the Reactome Pathways 2024 dataset.