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WNT5A Genewingless-type MMTV integration site family, member 5A The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
WNT5A-AS1 GeneWNT5A antisense RNA 1 |
wnt5a Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term wnt5a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
WNT5A Gene SetFrom Guide to Pharmacology Protein Ligands of Receptors receptors of the WNT5A ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset. |
WNT5A Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for WNT5A from the Pathway Commons Protein-Protein Interactions dataset. |
WNT5A Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the WNT5A gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
WNT5A-dependent internalization of FZD4 Gene Setproteins participating in the WNT5A-dependent internalization of FZD4 pathway from the Reactome Pathways dataset. |
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 Gene Setproteins participating in the WNT5A-dependent internalization of FZD2, FZD5 and ROR2 pathway from the Reactome Pathways dataset. |
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 Gene Setproteins participating in the WNT5A-dependent internalization of FZD2, FZD5 and ROR2 pathway from the Reactome Pathways 2024 dataset. |
WNT5A-dependent internalization of FZD4 Gene Setproteins participating in the WNT5A-dependent internalization of FZD4 pathway from the Reactome Pathways 2024 dataset. |