Name

NEFM Gene

neurofilament, medium polypeptide

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

NEFL Gene

neurofilament, light polypeptide

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]

NEFH Gene

neurofilament, heavy polypeptide

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008]

NEFHP1 Gene

neurofilament, heavy polypeptide pseudogene 1

NEFMP1 Gene

neurofilament, medium polypeptide pseudogene 1

NEFLP1 Gene

neurofilament, light polypeptide pseudogene 1

nef Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nef in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

hiv-1 nef: negative effector of fas and tnf Gene Set

From Biocarta Pathways

proteins participating in the hiv-1 nef: negative effector of fas and tnf pathway from the Biocarta Pathways dataset.

nefopam-3730 Gene Set

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the nefopam-3730 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

nefopam-3627 Gene Set

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the nefopam-3627 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

nefopam-2355 Gene Set

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the nefopam-2355 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

nefopam-2317 Gene Set

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the nefopam-2317 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

nefopam-4752 Gene Set

From CMAP Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the nefopam-4752 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

neferine Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical neferine from the curated CTD Gene-Chemical Interactions dataset.

Nefopam Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Nefopam from the curated CTD Gene-Chemical Interactions dataset.

nefazodone Gene Set

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical nefazodone from the curated CTD Gene-Chemical Interactions dataset.

Nefazodone Gene Set

From DrugBank Drug Targets

interacting proteins for the Nefazodone drug from the curated DrugBank Drug Targets dataset.

nefa Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nefa in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

nefh Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nefh in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

nefs Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nefs in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

nefmediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nefmediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

nefdependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nefdependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

neferinetreated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term neferinetreated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

nefspecific Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nefspecific in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

nefinduced Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nefinduced in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

nefindependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nefindependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

nefazodone Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the nefazodone ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

Nefazodone Gene Set

From HMDB Metabolites of Enzymes

interacting proteins for the Nefazodone metabolite from the curated HMDB Metabolites of Enzymes dataset.

NEFA-interacting nuclear protein NIP30, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NEFA-interacting nuclear protein NIP30, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NEFM Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NEFM from the Pathway Commons Protein-Protein Interactions dataset.

NEFL Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NEFL from the Pathway Commons Protein-Protein Interactions dataset.

NEFH Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NEFH from the Pathway Commons Protein-Protein Interactions dataset.

HIV-1 Nef: Negative effector of Fas and TNF-alpha Gene Set

From PID Pathways

proteins participating in the HIV-1 Nef: Negative effector of Fas and TNF-alpha pathway from the PID Pathways dataset.

Nef Mediated CD8 Down-regulation Gene Set

From Reactome Pathways

proteins participating in the Nef Mediated CD8 Down-regulation pathway from the Reactome Pathways dataset.

Nef mediated downregulation of CD28 cell surface expression Gene Set

From Reactome Pathways

proteins participating in the Nef mediated downregulation of CD28 cell surface expression pathway from the Reactome Pathways dataset.

Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters Gene Set

From Reactome Pathways

proteins participating in the Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters pathway from the Reactome Pathways dataset.

The role of Nef in HIV-1 replication and disease pathogenesis Gene Set

From Reactome Pathways

proteins participating in the The role of Nef in HIV-1 replication and disease pathogenesis pathway from the Reactome Pathways dataset.

Nef mediated downregulation of MHC class I complex cell surface expression Gene Set

From Reactome Pathways

proteins participating in the Nef mediated downregulation of MHC class I complex cell surface expression pathway from the Reactome Pathways dataset.

Nef and signal transduction Gene Set

From Reactome Pathways

proteins participating in the Nef and signal transduction pathway from the Reactome Pathways dataset.

Nef Mediated CD4 Down-regulation Gene Set

From Reactome Pathways

proteins participating in the Nef Mediated CD4 Down-regulation pathway from the Reactome Pathways dataset.

nef cell Gene Set

From TISSUES Text-mining Tissue Protein Expression Evidence Scores

proteins co-occuring with the tissue nef cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.