Harmonizome 3.0

soc-2 suppressor of clear homolog (C. elegans)

This gene encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream signal transducers in the RAS/ERK MAP kinase signaling cascade. Mutations in this gene have been associated with Noonan-like syndrome with loose anagen hair. [provided by RefSeq, May 2010]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term shoc2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for SHOC2 from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the SHOC2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From Reactome Pathways 2024

proteins participating in the SHOC2 M1731 mutant abolishes MRAS complex function pathway from the Reactome Pathways 2024 dataset.