Harmonizome 3.0

ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) pseudogene

ras-related C3 botulinum toxin substrate 1 pseudogene 5

This locus encodes one of the pseudogenes of the functional ras-related C3 botulinum toxin substrate 1 gene (RAC1, GeneID:5879) located on chr 7. It is intronless, shares overall 93% sequence identity with the RAC1 gene, and has enough differences in the coding region so as not to be able to code for a functional protein. There is no evidence of transcription at this pseudogene locus on chr 4. [provided by RefSeq, Jul 2008]

ras-related C3 botulinum toxin substrate 1 pseudogene 4

ras-related C3 botulinum toxin substrate 1 pseudogene 1

ras-related C3 botulinum toxin substrate 1 pseudogene 3

ras-related C3 botulinum toxin substrate 1 pseudogene 2

ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6. [provided by RefSeq, Jul 2013]

ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)

The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

ras-related C3 botulinum toxin substrate 1 pseudogene 9

ras-related C3 botulinum toxin substrate 1 pseudogene 8

ras-related C3 botulinum toxin substrate 1 pseudogene 6

ras-related C3 botulinum toxin substrate 1 pseudogene 7

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Botulinum Toxins from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Botulinum Toxins, Type A from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Toxins, Biological from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical Bacterial Toxins from the curated CTD Gene-Chemical Interactions dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term toxins in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Reactome Pathways 2014

proteins participating in the Uptake and actions of bacterial toxins pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Neurotoxicity of clostridium toxins pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Uptake and function of anthrax toxins pathway from the Reactome Pathways dataset.

From Reactome Pathways 2024

proteins participating in the Neurotoxicity of clostridium toxins pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Uptake and actions of bacterial toxins pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Uptake and function of anthrax toxins pathway from the Reactome Pathways 2024 dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical botulinum toxin type E from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical botulinum toxin type D from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical botulinum toxin type C from the curated CTD Gene-Chemical Interactions dataset.

From CTD Gene-Chemical Interactions

genes/proteins interacting with the chemical exoenzyme C3, Clostridium botulinum from the curated CTD Gene-Chemical Interactions dataset.

From DrugBank Drug Targets

interacting proteins for the Botulinum Toxin Type A drug from the curated DrugBank Drug Targets dataset.

From DrugBank Drug Targets

interacting proteins for the Botulinum Toxin Type B drug from the curated DrugBank Drug Targets dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term botulinum in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From PID Pathways

proteins participating in the Effects of Botulinum toxin pathway from the PID Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Toxicity of botulinum toxin type G (BoNT/G) pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Toxicity of botulinum toxin type F (BoNT/F) pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Toxicity of botulinum toxin type E (BoNT/E) pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Toxicity of botulinum toxin type D (BoNT/D) pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Toxicity of botulinum toxin type B (BoNT/B) pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Toxicity of botulinum toxin type C (BoNT/C) pathway from the Reactome Pathways dataset.

From Reactome Pathways 2014

proteins participating in the Toxicity of botulinum toxin type A (BoNT/A) pathway from the Reactome Pathways dataset.

From Reactome Pathways 2024

proteins participating in the Toxicity of botulinum toxin type A (botA) pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Toxicity of botulinum toxin type B (botB) pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Toxicity of botulinum toxin type C (botC) pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Toxicity of botulinum toxin type D (botD) pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Toxicity of botulinum toxin type E (botE) pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Toxicity of botulinum toxin type F (botF) pathway from the Reactome Pathways 2024 dataset.

From Reactome Pathways 2024

proteins participating in the Toxicity of botulinum toxin type G (botG) pathway from the Reactome Pathways 2024 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the BOTULINUM TOXIN TYPE A drug from theDGIdb Drug Targets 2026 dataset.

From DGIdb Drug Targets 2026

interacting proteins for the BOTULINUM TOXIN TYPE B drug from theDGIdb Drug Targets 2026 dataset.