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EDA Geneectodysplasin A The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
eda Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term eda in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
EDA Gene SetFrom Guide to Pharmacology Protein Ligands of Receptors receptors of the EDA ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset. |
EDA Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for EDA from the Pathway Commons Protein-Protein Interactions dataset. |
EDA Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the EDA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
EDA signaling in hair follicle development Gene SetFrom WikiPathways Pathways 2024 proteins participating in the EDA signaling in hair follicle development pathway from the WikiPathways Pathways 2024 dataset. |
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) Gene Setproteins participating in the IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) pathway from the Reactome Pathways 2024 dataset. |
IkBA variant leads to EDA-ID Gene Setproteins participating in the IkBA variant leads to EDA-ID pathway from the Reactome Pathways 2024 dataset. |