Name

EDA Gene

ectodysplasin A

The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

eda Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term eda in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

EDA Gene Set

From Guide to Pharmacology Protein Ligands of Receptors

receptors of the EDA ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset.

EDA Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for EDA from the Pathway Commons Protein-Protein Interactions dataset.

EDA Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the EDA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

EDA signaling in hair follicle development Gene Set

From WikiPathways Pathways 2024

proteins participating in the EDA signaling in hair follicle development pathway from the WikiPathways Pathways 2024 dataset.

IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) Gene Set

From Reactome Pathways 2024

proteins participating in the IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) pathway from the Reactome Pathways 2024 dataset.

IkBA variant leads to EDA-ID Gene Set

From Reactome Pathways 2024

proteins participating in the IkBA variant leads to EDA-ID pathway from the Reactome Pathways 2024 dataset.