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G6PD Geneglucose-6-phosphate dehydrogenase This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
g6pd Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term g6pd in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
G6PD Gene SetFrom NURSA Protein-Protein Interactions interacting proteins for G6PD from the NURSA Protein-Protein Interactions dataset. |
G6PD Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for G6PD from the Pathway Commons Protein-Protein Interactions dataset. |
G6PD Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the G6PD gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
G6PD Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the G6PD gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |
g6pd deficiency Gene SetFrom GAD Gene-Disease Associations genes associated with the disease g6pd deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
sickle cell anemia; g6pd deficiency Gene SetFrom GAD Gene-Disease Associations genes associated with the disease sickle cell anemia; g6pd deficiency in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
hemolytic anemia due to g6pd deficiency Gene SetFrom OMIM Gene-Disease Associations genes associated with the hemolytic anemia due to g6pd deficiency phenotype from the curated OMIM Gene-Disease Associations dataset. |
{resistance to malaria due to g6pd deficiency} Gene SetFrom OMIM Gene-Disease Associations genes associated with the {resistance to malaria due to g6pd deficiency} phenotype from the curated OMIM Gene-Disease Associations dataset. |
Anemia, Nonspherocytic Hemolytic, Due To G6Pd Deficiency Gene SetFrom DisGeNET Gene-Disease Associations genes associated with the disease Anemia, Nonspherocytic Hemolytic, Due To G6Pd Deficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. |
G6Pd Tomah Phenotype Gene SetFrom DisGeNET Gene-Phenotype Associations genes associated with the phenotype G6Pd Tomah Phenotype in GWAS and other genetic association datasets from the DisGeNET Gene-Phenotype Associations dataset. |
G6PD AS Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD AS phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD deficiency Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD deficiency phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD CHAT Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD CHAT phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD MAHI Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD MAHI phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD SASS Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD SASS phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD MEDITERRAN Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD MEDITERRAN phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD CAGLI Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD CAGLI phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD deficient hemolytic anemia Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD deficient hemolytic anemia phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD PORT Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD PORT phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD NASHVI Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD NASHVI phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD ANAH Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD ANAH phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD SANTIAGO DE C Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD SANTIAGO DE C phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD SEATTLE-L Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD SEATTLE-L phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD MOD Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD MOD phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD IOWA C Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD IOWA C phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD I Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD I phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD SPRINGFI Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD SPRINGFI phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD WALTER R Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD WALTER R phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD BEVERLY HI Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD BEVERLY HI phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD TO Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD TO phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD RIVERS Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD RIVERS phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD ANDA Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD ANDA phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD AGRIGE Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD AGRIGE phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD G Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD G phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD TAIWAN-HA Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD TAIWAN-HA phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD CAN Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD CAN phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD PUERTO LI Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD PUERTO LI phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD MAL Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD MAL phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD GASTO Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD GASTO phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD MINNES Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD MINNES phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD MAR Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD MAR phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD IERAPE Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD IERAPE phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD VIANGC Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD VIANGC phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD JA Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD JA phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD LOMA LI Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD LOMA LI phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD COIM Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD COIM phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD TAIWAN-HAKKA Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD TAIWAN-HAKKA phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD GUADALAJ Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD GUADALAJ phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD KERALA-KAL Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD KERALA-KAL phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD KER Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD KER phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD KAL Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD KAL phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD AU Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD AU phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD GA Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD GA phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD QUING Y Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD QUING Y phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD ORI Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD ORI phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD NANK Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD NANK phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD NEAPO Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD NEAPO phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD AVE Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD AVE phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD NAM Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD NAM phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD NILG Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD NILG phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |
G6PD COSE Gene SetFrom ClinVar Gene-Phenotype Associations 2025 genes associated with the G6PD COSE phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset. |