GDNF

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Results for "GDNF": 2 genes, 7 gene sets

Name
GDNF Gene glial cell derived neurotrophic factor This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The recombinant form of this protein, a highly conserved neurotrophic factor, was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. This protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Mutations in this gene may be associated with Hirschsprung disease and Tourette syndrome. This gene encodes multiple protein isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]
GDNF-AS1 Gene GDNF antisense RNA 1 (head to head)
gdnf Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term gdnf in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
GDNF Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for GDNF from the Pathway Commons Protein-Protein Interactions dataset.
[¹²⁵I]GDNF (rat) Gene Set From Guide to Pharmacology Chemical Ligands of Receptors receptors of the [¹²⁵I]GDNF (rat) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.
GDNF/GAS1 Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the GDNF/GAS1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.
GDNF RET signaling axis Gene Set From WikiPathways Pathways 2024 proteins participating in the GDNF RET signaling axis pathway from the WikiPathways Pathways 2024 dataset.
GDNF signaling Gene Set From WikiPathways Pathways 2024 proteins participating in the GDNF signaling pathway from the WikiPathways Pathways 2024 dataset.
[125I]GDNF (RAT) Gene Set From DGIdb Drug Targets 2026 interacting proteins for the [125I]GDNF (RAT) drug from theDGIdb Drug Targets 2026 dataset.