GLI2

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Results for "GLI2": 1 gene, 7 gene sets

Name
GLI2 Gene GLI family zinc finger 2 This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008]
gli2 Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term gli2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
GLI2 Gene Set From MotifMap Predicted Transcription Factor Targets target genes of the GLI2 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.
GLI2 Gene Set From Pathway Commons Protein-Protein Interactions interacting proteins for GLI2 from the Pathway Commons Protein-Protein Interactions dataset.
Gli2 Gene Set From JASPAR Predicted Mouse Transcription Factor Targets 2025 target genes of the Gli2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Mouse Transcription Factor Targets 2925 dataset.
GLI2 Gene Set From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the GLI2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.
Degradation of GLI2 by the proteasome Gene Set From Reactome Pathways 2014 proteins participating in the Degradation of GLI2 by the proteasome pathway from the Reactome Pathways dataset.
Degradation of GLI2 by the proteasome Gene Set From Reactome Pathways 2024 proteins participating in the Degradation of GLI2 by the proteasome pathway from the Reactome Pathways 2024 dataset.