Name

IL2RB Gene

interleukin 2 receptor, beta

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008]

il2rb Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il2rb in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

IL2RB Gene Set

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for IL2RB from the MSigDB Cancer Gene Co-expression Modules dataset.

IL2RB Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for IL2RB from the Pathway Commons Protein-Protein Interactions dataset.

IL2RB Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the IL2RB gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

IL2-IL2RA-IL2RB complex Gene Set

From CORUM Protein Complexes

proteins in the IL2-IL2RA-IL2RB complex protein complex from the CORUM Protein Complexes dataset.

il2rbeta Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term il2rbeta in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.